@article{286,
  author = {Jessica Brogdon and Ali Sie and Clarisse Dah and Lucienne Ouermi and Boubacar Coulibaly and Elodie Lebas and Lina Zhong and Cindi Chen and Thomas Lietman and Jeremy Keenan and Thuy Doan and Catherine Oldenburg},
  title = {Poultry Ownership and Genetic Antibiotic Resistance Determinants in the Gut of Preschool Children.},
  abstract = {<p>Zoonotic transmission is likely a pathway for antibiotic resistance. Data from a randomized trial of pediatric antibiotic administration were secondarily evaluated to determine if poultry ownership was significantly associated with the presence of gut genetic antibiotic resistance determinants among 118 children in Burkina Faso. Antimicrobial resistance (AMR) determinants were classified using DNA sequencing. We measured the relationship between genetic resistance determinants and chicken ownership using a logistic regression model adjusted for confounding variables. Children in households reporting poultry ownership had four times the odds of tetracycline resistance determinants in the gut compared with those without household poultry (OR: 4.08, 95% CI: 1.08-15.44, P = 0.04). There was no statistically significant difference found for other antibiotic classes. Understanding the origins of antibiotic resistance may help spur the development of interventions to combat the global AMR crisis.</p>
},
  year = {2021},
  journal = {Am J Trop Med Hyg},
  month = {2021 Mar 22},
  issn = {1476-1645},
  doi = {10.4269/ajtmh.20-1384},
  language = {eng},
}