@article{576, author = {Huy Tran and Thảo Hạ and Linh Hoang and Yen Tran and Kevin Ruder and Lina Zhong and Cindi Chen and YuHeng Liu and Danny Yu and Thomas Abraham and Armin Hinterwirth and Michael Deiner and Travis Porco and Thomas Lietman and Thuy Doan and Gerami Seitzman and SCORPIO Group}, title = {Coxsackievirus A24 Causing Acute Conjunctivitis in a 2023 outbreak in Vietnam.}, abstract = {

OBJECTIVES: To determine the causative pathogen during the 2023 conjunctivitis outbreak in Vietnam METHODS: RNA-sequencing was used to identify pathogens before and during the outbreak.

RESULTS: 24 patients with infectious conjunctivitis between March and October 2023 from Hai Yen Vision Institute in Vietnam were swabbed. Coxsackievirus A24v was the most common pathogen identified. Phylogenetic analysis of these strains demonstrates similarities to the Coxsackievirus identified in the 2022 India outbreak. Human adenovirus D was also circulating. Ocular findings of tearing, purulence, and itching were common in this outbreak.

CONCLUSIONS: Multiple viruses can co-circulate during conjunctivitis outbreaks. Hemorrhagic conjunctivitis, commonly associated with coxsackievirus conjunctivitis, was not a common clinical sign in this outbreak. Repeat genetic surveillance, with the notable inclusion of RNA virus detection strategies, is important for outbreak detection.

}, year = {2024}, journal = {Int J Infect Dis}, pages = {107133}, month = {2024 Jun 12}, issn = {1878-3511}, doi = {10.1016/j.ijid.2024.107133}, language = {eng}, }