@article{586,
  author = {Khumbo Kalua and Esther Misanjo and Thomas Lietman and Kevin Ruder and Lina Zhong and Cindi Chen and YuHeng Liu and Danny Yu and Thomas Abraham and Nathaniel Wu and Daisy Yan and Armin Hinterwirth and Thuy Doan and Gerami Seitzman},
  title = {Etiologies of Infectious Keratitis in Malawi.},
  abstract = {<p>Infectious keratitis is a leading cause of corneal blindness worldwide with little information known about causative etiologies in Malawi, Africa. This area is resource-limited with ophthalmologist and microbiology services. The Department of Ophthalmology at the Kamuzu College of Health Sciences in Blantyre, Malawi, is a participating site of an international corneal ulcer consortium, capriCORN (Comprehensive Analysis of Pathogens, Resistomes, and Inflammatory-markers in the CORNea). In this study, 50 patients with corneal ulcers were swabbed for pathogen identification using RNA-sequencing. Corneal trauma was reported in 41% and 19% of the patients worked in agriculture. A pathogen was identified in 58% of the cases. Fungal pathogens predominated, followed by viruses and bacteria. Aspergillus, Fusarium, HSV-1, and Gardnerella were the most common pathogens detected. 50% of patients reported treatment with an antibiotic before presentation. Pathogens unusual for infectious keratitis, such as Subramaniula asteroids, Aureobasidium pullulans, and Gardnerella vaginalis, were also detected.</p>
},
  year = {2024},
  journal = {Am J Trop Med Hyg},
  month = {2024 Jul 16},
  issn = {1476-1645},
  doi = {10.4269/ajtmh.24-0149},
  language = {eng},
}