@article{761,
  keywords = {AMR, MORDOR, Niger, childhood mortality, mass drug distribution},
  author = {Armin Hinterwirth and Cindi Chen and Daisy Yan and Lina Zhong and Zhaoxia Zhou and YuHeng Liu and Jeremy Keenan and Kieran O'Brien and Elodie Lebas and Travis Porco and Thomas Lietman and Thuy Doan},
  title = {Co-selection of genetic antibiotic resistance in  after repeated azithromycin mass drug administrations in Niger.},
  abstract = {<p>The spread of antibiotic resistance is a major concern in the setting of azithromycin mass drug distribution for childhood mortality. We performed long-read whole-genome sequencing and phenotypic resistance analysis on  isolated from the nasopharynx of Nigerien children from communities treated with either six twice-yearly azithromycin distributions or placebo. Here, we showed that co-selection for macrolide, tetracycline, and trimethoprim-sulfamethoxazole genetic resistance was detected with repeated azithromycin mass drug distributions.CLINICAL TRIALSThis study is registered with ClinicalTrials.gov as NCT02047981.</p>},
  year = {2025},
  journal = {Antimicrobial agents and chemotherapy},
  pages = {e0156225},
  month = {12/2025},
  issn = {1098-6596},
  doi = {10.1128/aac.01562-25},
  language = {eng},
}