TY - JOUR
KW - Azithromycin
KW - Humans
KW - Anti-Bacterial Agents
KW - Child, Preschool
KW - Infant
KW - Gastrointestinal Microbiome
KW - Macrolides
KW - Burkina Faso
AU - Catherine Oldenburg
AU - Armin Hinterwirth
AU - Ali Sie
AU - Boubacar Coulibaly
AU - Lucienne Ouermi
AU - Clarisse Dah
AU - Charlemagne Tapsoba
AU - Susie Cummings
AU - Lina Zhong
AU - Cindi Chen
AU - Samarpita Sarkar
AU - Till Bärnighausen
AU - Thomas Lietman
AU - Jeremy Keenan
AU - Thuy Doan
AB - <p>We evaluated the effect of systemic antibiotics (azithromycin, amoxicillin, cotrimoxazole, or placebo) on the gut resistome in children aged 6 to 59 months. Azithromycin and cotrimoxazole led to an increase in macrolide and sulfonamide resistance determinants. Resistome expansion can be induced with a single course of antibiotics.</p>

BT - Clin Infect Dis
DA - 2020 01 16
DO - 10.1093/cid/ciz455
IS - 3
J2 - Clin Infect Dis
LA - eng
N2 - <p>We evaluated the effect of systemic antibiotics (azithromycin, amoxicillin, cotrimoxazole, or placebo) on the gut resistome in children aged 6 to 59 months. Azithromycin and cotrimoxazole led to an increase in macrolide and sulfonamide resistance determinants. Resistome expansion can be induced with a single course of antibiotics.</p>

PY - 2020
SP - 525
EP - 527
T2 - Clin Infect Dis
TI - Gut Resistome After Oral Antibiotics in Preschool Children in Burkina Faso: A Randomized, Controlled Trial.
VL - 70
SN - 1537-6591
ER -