TY - JOUR AU - Ahmed Arzika AU - Ramatou Maliki AU - Amza Abdou AU - Alio Mankara AU - Abdoul Harouna AU - Catherine Cook AU - Armin Hinterwirth AU - Lee Worden AU - Lina Zhong AU - Cindi Chen AU - Kevin Ruder AU - Zhaoxia Zhou AU - Elodie Lebas AU - Kieran O'Brien AU - Catherine Oldenburg AU - Victoria Le AU - Benjamin Arnold AU - Travis Porco AU - Jeremy Keenan AU - Thomas Lietman AU - Thuy Doan AB -
We evaluated the gut resistome of children from communities treated with 10 twice-yearly azithromycin distributions. While the macrolide resistance remained higher in the azithromycin arm, the selection of non-macrolide resistance observed at earlier time points did not persist. Longitudinal resistance monitoring should be a critical component of mass distribution programs.
BT - Clin Infect Dis DA - 2021 May 26 DO - 10.1093/cid/ciab485 J2 - Clin Infect Dis LA - eng N2 -We evaluated the gut resistome of children from communities treated with 10 twice-yearly azithromycin distributions. While the macrolide resistance remained higher in the azithromycin arm, the selection of non-macrolide resistance observed at earlier time points did not persist. Longitudinal resistance monitoring should be a critical component of mass distribution programs.
PY - 2021 T2 - Clin Infect Dis TI - Gut resistome of preschool children after prolonged mass azithromycin distribution: a cluster-randomized trial. SN - 1537-6591 ER -