TY - JOUR
AU - Huy Tran
AU - Thảo Hạ
AU - Linh Hoang
AU - Yen Tran
AU - Kevin Ruder
AU - Lina Zhong
AU - Cindi Chen
AU - YuHeng Liu
AU - Danny Yu
AU - Thomas Abraham
AU - Armin Hinterwirth
AU - Michael Deiner
AU - Travis Porco
AU - Thomas Lietman
AU - Thuy Doan
AU - Gerami Seitzman
AU - SCORPIO Group
AB - <p><b>OBJECTIVES: </b>To determine the causative pathogen during the 2023 conjunctivitis outbreak in Vietnam METHODS: RNA-sequencing was used to identify pathogens before and during the outbreak.</p>

<p><b>RESULTS: </b>24 patients with infectious conjunctivitis between March and October 2023 from Hai Yen Vision Institute in Vietnam were swabbed. Coxsackievirus A24v was the most common pathogen identified. Phylogenetic analysis of these strains demonstrates similarities to the Coxsackievirus identified in the 2022 India outbreak. Human adenovirus D was also circulating. Ocular findings of tearing, purulence, and itching were common in this outbreak.</p>

<p><b>CONCLUSIONS: </b>Multiple viruses can co-circulate during conjunctivitis outbreaks. Hemorrhagic conjunctivitis, commonly associated with coxsackievirus conjunctivitis, was not a common clinical sign in this outbreak. Repeat genetic surveillance, with the notable inclusion of RNA virus detection strategies, is important for outbreak detection.</p>

BT - Int J Infect Dis
DA - 2024 Jun 12
DO - 10.1016/j.ijid.2024.107133
J2 - Int J Infect Dis
LA - eng
N2 - <p><b>OBJECTIVES: </b>To determine the causative pathogen during the 2023 conjunctivitis outbreak in Vietnam METHODS: RNA-sequencing was used to identify pathogens before and during the outbreak.</p>

<p><b>RESULTS: </b>24 patients with infectious conjunctivitis between March and October 2023 from Hai Yen Vision Institute in Vietnam were swabbed. Coxsackievirus A24v was the most common pathogen identified. Phylogenetic analysis of these strains demonstrates similarities to the Coxsackievirus identified in the 2022 India outbreak. Human adenovirus D was also circulating. Ocular findings of tearing, purulence, and itching were common in this outbreak.</p>

<p><b>CONCLUSIONS: </b>Multiple viruses can co-circulate during conjunctivitis outbreaks. Hemorrhagic conjunctivitis, commonly associated with coxsackievirus conjunctivitis, was not a common clinical sign in this outbreak. Repeat genetic surveillance, with the notable inclusion of RNA virus detection strategies, is important for outbreak detection.</p>

PY - 2024
EP - 107133
T2 - Int J Infect Dis
TI - Coxsackievirus A24 Causing Acute Conjunctivitis in a 2023 outbreak in Vietnam.
SN - 1878-3511
ER -