@article {1436,
	title = {Etiologies of Infectious Keratitis in Malawi.},
	journal = {Am J Trop Med Hyg},
	year = {2024},
	month = {2024 Jul 16},
	abstract = {<p>Infectious keratitis is a leading cause of corneal blindness worldwide with little information known about causative etiologies in Malawi, Africa. This area is resource-limited with ophthalmologist and microbiology services. The Department of Ophthalmology at the Kamuzu College of Health Sciences in Blantyre, Malawi, is a participating site of an international corneal ulcer consortium, capriCORN (Comprehensive Analysis of Pathogens, Resistomes, and Inflammatory-markers in the CORNea). In this study, 50 patients with corneal ulcers were swabbed for pathogen identification using RNA-sequencing. Corneal trauma was reported in 41\% and 19\% of the patients worked in agriculture. A pathogen was identified in 58\% of the cases. Fungal pathogens predominated, followed by viruses and bacteria. Aspergillus, Fusarium, HSV-1, and Gardnerella were the most common pathogens detected. 50\% of patients reported treatment with an antibiotic before presentation. Pathogens unusual for infectious keratitis, such as Subramaniula asteroids, Aureobasidium pullulans, and Gardnerella vaginalis, were also detected.</p>
},
	issn = {1476-1645},
	doi = {10.4269/ajtmh.24-0149},
	author = {Kalua, Khumbo and Misanjo, Esther S and Lietman, Thomas M and Ruder, Kevin and Zhong, Lina and Chen, Cindi and Liu, YuHeng and Yu, Danny and Abraham, Thomas and Wu, Nathaniel and Yan, Daisy and Hinterwirth, Armin and Doan, Thuy and Seitzman, Gerami D}
}
