@article {1376, title = {Acute neuroretinitis as a delayed manifestation of tubulointerstitial nephritis and uveitis syndrome.}, journal = {Am J Ophthalmol Case Rep}, volume = {34}, year = {2024}, month = {2024 Jun}, pages = {102050}, abstract = {

PURPOSE: Tubulointerstitial nephritis syndrome with uveitis (TINU) is a rare, acquired syndrome characterized by interstitial nephritis with bilateral uveitis. We report a case of TINU with typical bilateral anterior uveitis complicated by an atypical, delayed-onset neuroretinitis in a 12-year old patient.

OBSERVATION: A 12-year-old female with a 21-month history of TINU featuring chronic bilateral anterior uveitis presented with one week of blurred vision in her left eye. On exam she was found to have new-onset disc edema in the right eye and neuroretinitis in the left eye. After a negative infectious disease workup, the patient was treated with a course of intravenous (IV) solumedrol with prednisone taper and advancement of her systemic immunosuppression. In follow up she demonstrated resolution of her disc edema and neuroretinitis with improved visual acuity and clinical exam.

CONCLUSION: This case stresses the importance of monitoring for additional ocular manifestations including neuroretinitis years after the onset of anterior uveitis in TINU. In comparison to the two published cases of TINU with neuroretinitis, this case shares features of uveitis progression, and thus highlights the value of further description of TINU-associated neuroretinitis.

}, issn = {2451-9936}, doi = {10.1016/j.ajoc.2024.102050}, author = {Vazquez, Sara E and Niemeyer, Katherine and Mentreddy, Akshay and Gonzales, John and Rasool, Nailyn and Acharya, Nisha R and Doan, Thuy and Shantha, Jessica G} } @article {846, title = {Detection of Tropheryma whipplei Genome From the Aqueous Humor by Metagenomic Sequencing.}, journal = {Ann Intern Med}, year = {2021}, month = {06/2021}, issn = {1539-3704}, doi = {10.7326/L20-1470}, author = {Gonzales, John A and Doan, Thuy and VanZante, Annemieke and Stewart, Jay M and Sura, Amol and Reddy, Amit and Rasool, Nailyn} }