| Title | Gut resistome of preschool children after prolonged mass azithromycin distribution: a cluster-randomized trial. |
| Publication Type | Journal Article |
| Year of Publication | 2021 |
| Authors | Arzika AM, Maliki R, Abdou A, Mankara AK, Harouna AN, Cook C, Hinterwirth A, Worden L, Zhong L, Chen C, Ruder K, Zhou Z, Lebas E, O'Brien KS, Oldenburg CE, Le V, Arnold BF, Porco T, Keenan JD, Lietman TM, Doan T |
| Journal | Clin Infect Dis |
| Date Published | 2021 May 26 |
| ISSN | 1537-6591 |
| Abstract | We evaluated the gut resistome of children from communities treated with 10 twice-yearly azithromycin distributions. While the macrolide resistance remained higher in the azithromycin arm, the selection of non-macrolide resistance observed at earlier time points did not persist. Longitudinal resistance monitoring should be a critical component of mass distribution programs. |
| DOI | 10.1093/cid/ciab485 |
| Alternate Journal | Clin Infect Dis |
| PubMed ID | 34037753 |