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ACTION was a research study to determine if taking a medication called azithromycin can help treat COVID-19 disease.
This randomized controlled trial evaluates the effect of topical antibiotics on the local ocular surface resistome and microbiome and other systemic sites including the nasopharynx, mouth, and gut.
Comprehensive Analysis of Pathogens, Resistomes, and Inflammatory-markers in the CORNea (CapriCORN)
Uveitis is a significant cause of blindness globally and there are many challenges to diagnose infectious etiologies. We will collaborate with stakeholders both local and international to enhance the understanding of the pathogenesis of ocular inflammatory diseases to improve upon classification, diagnosis, biomarker identification, and evaluate the host response.
These large randomized controlled trials evaluate the effect of mass drug distribution to improve childhood mortality in Niger and Burkina Faso.
This multi-site randomized controlled trial is designed to compare metagenomic deep sequencing (MDS) versus standard of care testing for improvement of outcomes for intraocular infections.
The Proctor Foundation was founded in 1947 with the aim of trachoma eradication. The laboratory works closely with Proctor faculty members to design, optimize, and implement molecular assays to improve surveillance and treatment paradigms.
SCORPIO is an international, multi-site study that takes advantage of advances in genomic technologies to enhance our understanding of conjunctivitis epidemics globally by identifying the pathogens involved, characterizing the evolution of pathogen genomes across time and space, and defining the immune responses to these infections.
Work from the Doan Lab would not have been possible without generous support.