Vaccine-Associated Measles Encephalitis in Immunocompromised Child, California, USA.

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TitleVaccine-Associated Measles Encephalitis in Immunocompromised Child, California, USA.
Publication TypeJournal Article
Year of Publication2022
AuthorsCostales C, Sahoo MK, Huang CH, Guimaraes CV, Born D, Kushner L, Gans HA, Doan TA, Pinsky BA
JournalEmerg Infect Dis
Volume28
Issue4
Pagination906-908
Date Published2022 Apr
ISSN1080-6059
Abstract

We report a fatal case of vaccine-associated measles encephalitis in an immunocompromised child in California, USA. The infection was confirmed by whole-genome RNA sequencing of measles virus from brain tissue. We observed biased matrix-gene hypermutation consistent with persistent measles virus central nervous system infection.
DOI10.3201/eid2804.212357
Alternate JournalEmerg Infect Dis
PubMed ID35318930