Ocular Pathogen and Transcriptome Investigation
using Comprehensive Sequencing


This multi-site randomized controlled trial is designed to compare metagenomic deep sequencing (MDS) versus standard of care testing for improvement of outcomes for intraocular infections.

Study Team

  • Thuy Doan, MD, PhD (PI)
  • Jessica Shantha, MD, MAS (MPI)
  • Ben Arnold, PhD, MPH
  • Nisha Acharya, MD, MS
  • Travis Porco, MD, MPH
  • Tom Lietman, MD
  • Armin Hinterwirth, PhD
  • Wendy Ao, BS
  • Cindi Chen, MS


  • Kareem Moussa, MD; University of California, Davis (UCD)
  • Edmund Tsui, MD; University of California, Los Angeles (UCLA)
  • Steven Yeh, MD;  University of Nebraska
  • Al Vitale, MD, PhD; University of Utah
  • Akbar Shakoor, MD; University of Utah
  • Wipada Laovirojjanakul, MD; Khon Kaen University, Thailand
  • Thanapong Somkijrungroj, MD; Chulalongkorn University, Thailand
  • Wijak Kongwattananon, MD; Chulalongkorn University, Thailand